When editing Native Instruments Pro-53 patches, knob settings are changed by clicking on the control, then moving your mouse up or down to change the value. If you find that you cannot zero in on the setting you want, you can hold down the SHIFT key while clicking on a knob. This allows you to enter a mode whereby you have extra-fine control over the knob values. When holding down the Shift key, you will effectively need to increase the mouse movement that is required to turn the knob and set the exact value.